Pediatric refractory and super-refractory status epilepticus
نویسندگان
چکیده
منابع مشابه
Ketogenic diet treatment for pediatric super-refractory status epilepticus
PURPOSE We aimed to study whether ketogenic diet (KD) therapy leads to resolution of super-refractory status epilepticus in pediatric patients without significant harm. METHOD A retrospective review was performed at Phoenix Children's Hospital on patients with super-refractory status epilepticus undergoing ketogenic diet therapy from 2011 to 2015. RESULTS Ten children with super-refractory ...
متن کاملBRIEF COMMUNICATION Pediatric Super-Refractory Status Epilepticus Treated with Allopregnanolone
Super-refractory status epilepticus is a life-threatening condition. Resistance to benzodiazepine and barbiturate treatment for this disorder is thought to be due to internalization of synaptic c-aminobutyric acid (GABA)A receptors, and withdrawal of benzodiazepines and barbiturates during treatment often triggers seizure recurrence. The neurosteroid allopregnanolone acts as a positive alloster...
متن کاملPediatric super-refractory status epilepticus treated with allopregnanolone.
Super-refractory status epilepticus is a life-threatening condition. Resistance to benzodiazepine and barbiturate treatment for this disorder is thought to be due to internalization of synaptic γ-aminobutyric acid (GABA)A receptors, and withdrawal of benzodiazepines and barbiturates during treatment often triggers seizure recurrence. The neurosteroid allopregnanolone acts as a positive alloster...
متن کاملHow Refractory is Super-Refractory Status Epilepticus- A Personal View!
The word, super-refectory is coined recently in status epilepticus (SE) when the seizures continue unabated for a day or more, despite rigorous management , leading to subsequent neuronal injury, most of the times and even death [1]. The SuperRefractory Status Epilepeticus is a rare but not uncommon type of ongoing seizure activity and the exact pathophysiology is still not yet studied well. Th...
متن کاملKetogenic Diet in Super-Refractory Status Epilepticus
Researchers from the Children's National Health System in Washington, D.C. studied the feasibility, rate of complications, and effect on seizures of initiating the Ketogenic Diet (KD) in pediatric patients with Super-Refractory Status Epilepticus (SRSE).
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ژورنال
عنوان ژورنال: Seizure
سال: 2019
ISSN: 1059-1311
DOI: 10.1016/j.seizure.2018.05.012